A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.
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Commun Biol (2022) doi:10.1038/s42003-022-03630-3.
Inactivated whole influenza virus particle vaccines induce neutralizing antibodies with an increase in immunoglobulin gene subclones of B-lymphocytes in cynomolgus macaques.
Masanori Shiohara, Saori Suzuki, Shintaro Shichinohe, Hirohito Ishigaki, Misako Nakayama, Naoki Nomura, Masashi Shingai, Toshiki Sekiya, Marumi Ohno, Sayaka Iida, Naoko Kawai, Mamiko Kawahara, Junya Yamagishi, Kimihito Ito, Ryotarou Mitsumata, Tomio Ikeda, Kenji Motokawa, Tomoyoshi Sobue, Yasushi Itoh.
Vaccine (2022) doi: 10.1016/j.vaccine.2022.05.045.
Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses.
Tomokazu Tamura, Shiho Torii, Kentaro Kajiwara, Itsuki Anzai, Yoichiro Fujioka , Kisho Noda, Shuhei Taguwa, Yuhei Morioka, Rigel Suzuki, Yuzy Fauzyah, Chikako Ono, Yusuke Ohba, Masato Okada, Takasuke Fukuhara, and Yoshiharu Matsuura.
PLoS Pathog (2022) doi:10.1101/2021.10.25.465714.
Characterization of H9N2 Avian Influenza Viruses Isolated from Poultry Products in a Mouse Model.
Jurika Murakami, Akihiro Shibata, Gabriele Neumann, Masaki Imai, Tokiko Watanabe, and Yoshihiro Kawaoka.
Viruses (2022) doi:10.3390/v14040728.
Co-administration of Favipiravir and the Remdesivir Metabolite GS-441524 Effectively Reduces SARS-CoV-2 Replication in the Lungs of the Syrian Hamster Model.
Shiho Chiba, Maki Kiso, Noriko Nakajima, Shun Iida, Tadashi Maemura, Makoto Kuroda, Yuko Sato, Mutsumi Ito, Moe Okuda, Shinya Yamada, Kiyoko Iwatsuki-Horimoto, Tokiko Watanabe, Masaki Imai, Tammy Armbrust, RalphS Baric, Peter J Halfmann, Tadaki Suzuki, and Yoshihiro Kawaoka.
mBio (2022) doi:10.1128/mbio.03044-21.
SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response.
Shunya Tsuji, Shohei Minami, Rina Hashimoto, Yusuke Konishi, Tatsuya Suzuki, Tamae Kondo, Miwa Sasai, Shiho Torii, Chikako Ono, Shintaro Shichinohe, Shintaro Sato, Masahiro Wakita, Shintaro Okumura, Sosuke Nakano, Tatsuyuki Matsudaira, Tomonori Matsumoto, Shimpei Kawamoto, Masahiro Yamamoto, Tokiko Watanabe, Yoshiharu Matsuura, Kazuo Takayama, Takeshi Kobayashi, Toru Okamoto, and Eiji Hara.
Nat Aging (2022) doi:10.1038/s43587-022-00170-7.